Preparation of 7-deoxyspectinomycin and 7-deoxy-8-epi-4(R)-dihydrospectinomycin.
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Preparation of 7-epi-cephalosporin derivatives.
position 6,1-4) the preparation of 7-epi-aminocephalosporanic 'acid (7a-ACA) has thus far not been reported. Some 7-epi-cephalosporins have been prepared by base-catalyzed epimerization of cephalosporin sulfoxidesu or acidcatalyzed ring expansion of 6-epi-penicillins.e) Both procedures, however, are not convenient for the preparation of 7-epi-cephalosporin derivatives. We wish to report the direct
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【Introduction】 8-Oxo-2 ́-deoxyguanosine (8-oxo-dG) is a representative nucleoside damage that is formed by oxidation of 2 ́-deoxyguanosine (dG) with reactive oxygen species (ROS), and its presence has been linked to aging, cancer, etc [1]. Unlike dG, 8-oxo-dG forms stable base pairs with both 2 ́-deoxycytidine (dC) and 2 ́-deoxyadenosine (dA). Based on the base-pairing properties of 8-oxo-dG, DNA p...
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The enantioselective synthesis of 7-epi-incarvilline for formal syntheses of (-)-incarvilline, (+)-incarvine C, and (-)-incarvillateine is described. The key features of our synthesis involve (1) stereoselective construction of the optically active bicyclic lactone utilizing Pd(0)-catalyzed allylic alkylation, (2) efficient transformation of the bridged bicyclic lactone to the key bicyclic lact...
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25 Regions selective for faces, places, and bodies feature prominently in the literature on 26 the human ventral visual pathway. Are selectivities for these categories in fact the most 27 robust response profiles in this pathway, or is their prominence an artifact of biased 28 sampling of the hypothesis space in prior work? Here we use a data-driven structure 29 discovery method that avoids the...
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26 Objective: to assess the association between functional limitations related to mobility and urinary 27 incontinence (UI) in elderly women. 28 Design: observational cross-sectional study. 29 Setting: 9 “balance” workshops in France. 30 Population: 1942 community-dwelling women aged 75-85 years, who were invited, based on voter 31 registration lists, to a "balance assessment". 32 Methods: Mobi...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1979
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.32.418